Description

2-Methylacetoacetic Acid is a versatile β-keto acid derivative that serves as a critical building block in organic synthesis. Its reactive methylene and carbonyl groups make it a valuable precursor for constructing complex molecular frameworks, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and manufacturers in the fine chemical, pharmaceutical intermediate, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of various active pharmaceutical ingredients (APIs), including potential cardiovascular and central nervous system drugs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators due to its ability to form heterocyclic structures.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and complex organic molecules requiring specific acetylacetone-like chemistry.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating novel compound libraries.
• Coordination Chemistry: Can act as a ligand or precursor for metal-organic frameworks (MOFs) and catalysts.
• Flavor & Fragrance Intermediate: Used in the synthesis of certain aroma chemicals and flavoring agents.

Basic Information

Product Name	2-Methylacetoacetic Acid
CAS No.	2382-59-4
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	2-Methyl-3-oxobutanoic Acid; 3-Oxo-2-methylbutyric Acid; 2-Methylacetoacetate; α-Methylacetoacetic Acid; 2-Methyl-3-oxobutyric Acid; Methylacetoacetic Acid; 3-Oxovaleric Acid (less common); 2-Methyl-β-ketobutyric Acid
EINECS	219-186-5

Quality Control

Our 2-Methylacetoacetic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including purity assay and impurity profiling, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment. We adhere to cGMP principles where applicable to guarantee consistent quality and reliable supply for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	60 - 65 °C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.