Description

2-(3,4-Dimethylphenyl)Hexafluoroisopropanol is a specialized fluorinated alcohol derivative, serving as a critical building block and intermediate in advanced organic synthesis. Its unique structure, featuring a hexafluoroisopropanol group attached to a dimethylphenyl ring, provides valuable properties such as enhanced acidity, lipophilicity, and stability, making it indispensable for creating high-performance materials and active compounds. This compound is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorine-containing compounds essential in electronic display technologies, enhancing charge transport and stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, improving chemical resistance, reducing surface energy, and creating specialty coatings.
• Catalyst & Ligand Design: Acts as a component in chiral ligands and organocatalysts for asymmetric synthesis, leveraging its steric and electronic properties.
• Analytical Chemistry & Research: Used as a standard or reagent in method development and fundamental research on fluorinated organic molecules.

Basic Information

Product Name	2-(3,4-Dimethylphenyl)Hexafluoroisopropanol
CAS No.	2379-17-1
Molecular Formula	C11H10F6O
Molecular Weight	272.19 g/mol
Synonyms	2-(3,4-Dimethylphenyl)-1,1,1,3,3,3-Hexafluoro-2-propanol; 1,1,1,3,3,3-Hexafluoro-2-(3,4-dimethylphenyl)propan-2-ol; α-(3,4-Dimethylphenyl)-α-(trifluoromethyl)-1,1,1,3,3,3-hexafluoro-2-propanol; 3,4-Dimethyl-α-(trifluoromethyl)benzenemethanol, 1,1,1,3,3,3-hexafluoro deriv.; Hexafluoro-2-(3,4-dimethylphenyl)isopropanol; 2379-17-1; 2-(3,4-Xylyl)hexafluoroisopropanol
EINECS	Contact for details

Quality Control

Our 2-(3,4-Dimethylphenyl)Hexafluoroisopropanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.