Description

1,4-Bis(Trifluoromethyl)-2,5-Dibromobenzene is a high-value, multi-functional aromatic building block featuring both bromine and trifluoromethyl substituents. This compound is essential for introducing fluorinated aromatic motifs and serving as a versatile coupling partner in advanced organic synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for targets requiring enhanced metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the trifluoromethyl group improves biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a core building block for fluorinated aromatic components in electronic display and lighting materials.
• Polymer & Specialty Chemicals: Incorporated into high-performance polymers, coatings, and resins to impart unique chemical resistance and thermal stability.
• Cross-Coupling Reactions: The bromine atoms make it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Organic Synthesis & Research: A versatile reagent for academic and industrial research in developing new fluorination methodologies and exploring structure-activity relationships.

Basic Information

Product Name	1,4-Bis(Trifluoromethyl)-2,5-Dibromobenzene
CAS No.	2375-96-4
Molecular Formula	C8H2Br2F6
Molecular Weight	371.91 g/mol
Synonyms	2,5-Dibromo-1,4-bis(trifluoromethyl)benzene; 1,4-Di(trifluoromethyl)-2,5-dibromobenzene; 2,5-Dibromo-α,α,α,α',α',α'-hexafluoro-p-xylene; Benzene, 1,4-bis(trifluoromethyl)-2,5-dibromo-; p-Xylene, α,α,α,α',α',α'-hexafluoro-2,5-dibromo-; 2375-96-4; NSC 163082
EINECS	Contact for details

Quality Control

Our 1,4-Bis(Trifluoromethyl)-2,5-Dibromobenzene is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.