Description

1-Chloro-1,1-Difluoro-2,4-Pentanedione is a specialized fluorinated diketone derivative, serving as a versatile and high-value building block in advanced chemical synthesis. Its unique structure, featuring both chloro and difluoro substituents, makes it a critical precursor for introducing fluorinated motifs into target molecules, enhancing their properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated active pharmaceutical ingredients (APIs), where fluorine atoms are used to modulate metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in creating novel fluorinated pesticides and herbicides, leveraging fluorine's ability to improve lipophilicity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, coatings, and electronic materials with enhanced chemical and thermal resistance.
• Organic Synthesis Building Block: Employed in various name reactions for constructing complex organic molecules, particularly in nucleophilic substitution and condensation reactions facilitated by its reactive carbonyl and halogen groups.
• Ligand and Catalyst Development: Utilized in the preparation of fluorinated ligands for metal-organic frameworks (MOFs) or catalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: A valuable reagent for academic and industrial R&D focused on exploring new fluorination methodologies and the structure-activity relationships of fluorinated compounds.

Basic Information

Product Name	1-Chloro-1,1-Difluoro-2,4-Pentanedione
CAS No.	2375-76-0
Molecular Formula	C5H5ClF2O2
Molecular Weight	170.54 g/mol
Synonyms	1-Chloro-1,1-difluoropentane-2,4-dione; 1-Chloro-1,1-difluoroacetylacetone; Chlorodifluoroacetylacetone; 2,4-Pentanedione, 1-chloro-1,1-difluoro-; 1,1-Difluoro-1-chloro-2,4-pentanedione; 1-Chloro-1,1-difluoro-2,4-dioxopentane
EINECS	Contact for details

Quality Control

Our 1-Chloro-1,1-Difluoro-2,4-Pentanedione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Due to its reactivity as a strong acid/organic solvent, appropriate secondary containment is recommended. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.