Description

3-[[9-[(2,2,2-Trifluoroacetyl)Amino]-9H-Fluoren-2-Yl]Carbamoyl]Prop-2- Enoic Acid CAS NO 2341-42-6 is a high-purity, multifunctional chemical building block featuring a fluorene core modified with a trifluoroacetyl-protected amino group and a carboxylic acid terminus. This compound matters for its role as a key synthetic intermediate in the development of advanced materials and active pharmaceutical ingredients (APIs), where its unique structure enables precise molecular design. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex organic molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging its fluorene-based aromatic system.
• Material Science: Acts as a monomer or precursor for advanced polymers, liquid crystals, and organic electronic materials due to its rigid, planar structure.
• Fluorescent Probe Synthesis: The fluorene moiety makes it a suitable starting point for creating dyes and fluorescent tags for bioimaging and diagnostic assays.
• Peptide Mimetics & Conjugation: The carboxylic acid and protected amine functionalities allow for its use in peptide synthesis and bioconjugation chemistry.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex heterocycles and functionalized aromatic compounds.

Basic Information

Product Name	3-[[9-[(2,2,2-Trifluoroacetyl)Amino]-9H-Fluoren-2-Yl]Carbamoyl]Prop-2- Enoic Acid
CAS No.	2341-42-6
Molecular Formula	C19H13F3N2O4
Molecular Weight	390.31 g/mol
Synonyms	2-Propenoic acid, 3-[[9-[(2,2,2-trifluoroacetyl)amino]-9H-fluoren-2-yl]amino]-3-oxo-; 3-({9-[(2,2,2-Trifluoroacetyl)amino]-9H-fluoren-2-yl}carbamoyl)acrylic acid; N-(9H-Fluoren-2-yl)-2,2,2-trifluoroacetamide-2'-acrylamide; 2'-Acrylamido-9-(2,2,2-trifluoroacetamido)fluorene; Fluorene-2-carboxamide, N-(2-carboxyethenyl)-9-[(trifluoroacetyl)amino]-; TFA-Fluorene-Acrylic Acid; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and manufacturing. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system suitable for supplying materials for cGMP and non-GMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.