Description

2,4'-Difluorobiphenyl is a high-purity fluorinated biphenyl derivative, a key organic intermediate prized for its unique electronic and steric properties. This compound is essential for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where precise molecular architecture is required. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical, agrochemical, and liquid crystal industries.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the stability of the fluorinated biphenyl core.
• Liquid Crystal Materials: Serves as a core structure in the development of fluorinated liquid crystals for high-performance displays.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials and host matrices in OLED devices.
• Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced thermal and chemical resistance.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	2,4'-Difluorobiphenyl
CAS No.	2285-28-1
Molecular Formula	C₁₂H₈F₂
Molecular Weight	190.19 g/mol
Synonyms	2,4'-Difluorodiphenyl; 1-Fluoro-2-(4-fluorophenyl)benzene; Biphenyl, 2,4'-difluoro-; 2-(4-Fluorophenyl)fluorobenzene; [1,1'-Biphenyl]-2,4'-diol, difluoro derivative; 4-Fluorophenyl-2-fluorobenzene
EINECS	218-928-6

Quality Control

Every batch of our 2,4'-Difluorobiphenyl is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by GC, HPLC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	38 - 42 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.