Description

2-Amino-3-Hydroxy-1-(4-Nitrophenyl)-1-Propanone is a specialized organic compound featuring both amino and hydroxy functional groups on a propanone backbone attached to a nitrophenyl ring. This unique structure makes it a valuable key chiral intermediate and building block in sophisticated organic synthesis. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs) and other high-value compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of chiral drugs, particularly β-blockers and other cardiovascular or neurological agents.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or plant growth regulators where its nitro and amino groups contribute to biological activity.
• Dye and Pigment Synthesis: Acts as an intermediate for creating azo dyes and other complex colorants, leveraging the reactive nitrophenyl group.
• Academic and R&D Laboratories: Employed in methodological studies, asymmetric synthesis, and catalysis research due to its multifunctional, chiral nature.
• Fine Chemical Production: Utilized as a building block for manufacturing complex molecules used in electronics, materials science, and specialty polymers.

Basic Information

Product Name	2-Amino-3-Hydroxy-1-(4-Nitrophenyl)-1-Propanone
CAS No.	2280-37-7
Molecular Formula	C9H10N2O4
Molecular Weight	210.19 g/mol
Synonyms	1-(4-Nitrophenyl)-2-amino-3-hydroxy-1-propanone; 2-Amino-3-hydroxy-1-(4-nitrophenyl)propan-1-one; 3-Amino-2-hydroxy-1-(4-nitrophenyl)-1-propanone; 4-Nitro-α-(aminomethyl)vanillyl ketone; NSC 403697; (RS)-2-Amino-3-hydroxy-1-(4-nitrophenyl)propan-1-one; (±)-2-Amino-3-hydroxy-1-(4-nitrophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Hydroxy-1-(4-Nitrophenyl)-1-Propanone is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.