Description

22,25-Diazacholestanol is a synthetic, nitrogen-containing steroidal derivative, a structural analog of cholesterol. This compound is of significant interest in advanced organic synthesis and pharmaceutical research, particularly for the development of novel bioactive molecules and enzyme inhibitors. It serves as a key chiral intermediate and building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel steroidal drugs, hormone analogs, and enzyme inhibitors targeting metabolic pathways.
• Biochemical Research: Used as a molecular probe or standard in studies of cholesterol metabolism, membrane biology, and sterol-protein interactions.
• Organic Synthesis Building Block: Provides a complex, functionalized steroidal core for constructing libraries of compounds in medicinal chemistry and drug discovery programs.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Material Science Research: Investigated for potential use in the development of advanced organic materials and liquid crystals due to its rigid molecular framework.

Basic Information

Product Name	22,25-Diazacholestanol
CAS No.	2278-46-8
Molecular Formula	C₂₇H₄₈N₂O
Molecular Weight	416.69 g/mol
Synonyms	22,25-Diaza-5-cholesten-3β-ol; 3β-Hydroxy-22,25-diazacholestane; 22,25-Diazacholest-5-en-3-ol; (3β)-22,25-Diaza-5-cholesten-3-ol; Steroidal diaza derivative; Cholestanol diaza analog
EINECS	Contact for details

Quality Control

Our 22,25-Diazacholestanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.