Description

2,2,2',4'-Tetrachloroacetophenone is a specialized halogenated aromatic ketone of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique substitution pattern makes it a valuable precursor for researchers and manufacturers in fine chemical, pharmaceutical intermediate, and material science industries.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its reactive carbonyl and halogen groups.
• Fine Chemical Building Block: Employed in custom synthesis and research for creating complex organic molecules, dyes, and pigments.
• Material Science Research: Acts as a monomer or cross-linking agent precursor in the development of specialty polymers and advanced materials.
• Chemical Research & Development: Utilized in academic and industrial R&D for methodological studies in halogenation, Friedel-Crafts acylation, and other organic transformations.

Basic Information

Product Name	2,2,2',4'-Tetrachloroacetophenone
CAS No.	2274-66-0
Molecular Formula	C8H4Cl4O
Molecular Weight	261.93 g/mol
Synonyms	1-(2,4-Dichlorophenyl)-2,2,2-trichloroethanone; 2,2,2-Trichloro-1-(2,4-dichlorophenyl)ethanone; α,α,α,2'-Tetrachloroacetophenone; NSC 406079; 2,4-Dichloro-α,α,α-trichloroacetophenone; Acetophenone, 2,2,2',4'-tetrachloro-
EINECS	218-892-7

Quality Control

Our 2,2,2',4'-Tetrachloroacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for synthesis and research applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.