Description

α-Amino-2,3-Dihydro-2-Oxooxazole-5-Acetic Acid is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique oxazole-acetic acid structure, which serves as a versatile precursor for the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of complex drug candidates and fine chemicals.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for compounds targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Serves as a critical scaffold for constructing novel heterocyclic libraries in drug discovery programs for high-throughput screening.
• Peptidomimetics: Used in the synthesis of peptide analogs and mimetics, where its structure can mimic natural amino acids to enhance stability or bioavailability.
• Agrochemical Synthesis: Employed as a building block for developing new generation herbicides and plant growth regulators with specific modes of action.
• Bioconjugation Chemistry: The reactive amino and carboxylic acid groups facilitate its use in linking molecules, such as in antibody-drug conjugate (ADC) linker technology.
• Academic & Industrial R&D: Fundamental research reagent for studying heterocyclic reaction mechanisms and developing new synthetic methodologies.

Basic Information

Item	Detail
Product Name	α-Amino-2,3-Dihydro-2-Oxooxazole-5-Acetic Acid
CAS No.	2255-39-2
Molecular Formula	C5H6N2O4
Molecular Weight	158.11 g/mol
Synonyms	5-Oxazoleacetic acid, α-amino-2,3-dihydro-2-oxo-; (Aminooxooxazolidinyl)acetic acid; 2-Amino-2-(2-oxo-2,3-dihydrooxazol-5-yl)acetic acid; L-2-Amino-3-(2-oxo-2,3-dihydrooxazol-5-yl)propanoic acid derivative; Oxazole-5-acetic acid, α-amino-2,3-dihydro-2-oxo-; 2255-39-2; NSC 163063
EINECS	Contact for details

Quality Control

We supply α-Amino-2,3-Dihydro-2-Oxooxazole-5-Acetic Acid in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere if necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.