Description

1-(Trifluoromethyl)Vinyl Acetate is a versatile fluorinated building block characterized by its reactive vinyl acetate moiety and trifluoromethyl group. This compound is valued for its ability to introduce both fluorine and polymerizable functionality into target molecules, enhancing properties like chemical stability, lipophilicity, and material performance. It is primarily sought by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the trifluoromethyl group into drug candidates to improve metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where fluorine atoms enhance biological activity and environmental persistence.
• Fluoropolymer Modification: Serves as a co-monomer or grafting agent to incorporate fluorinated segments into polymers, improving oil, solvent, and chemical resistance.
• Organic Electronics: Employed in the synthesis of fluorinated organic semiconductors and dielectric materials for OLEDs and thin-film transistors.
• Surface Coatings & Resins: Imparts low surface energy and enhanced durability in specialty coatings, adhesives, and sealants.
• Cross-coupling Reactions: Acts as an electrophilic partner in Pd-catalyzed reactions for constructing complex fluorinated architectures.

Basic Information

Product Name	1-(Trifluoromethyl)Vinyl Acetate
CAS No.	2247-91-8
Molecular Formula	C5H5F3O2
Molecular Weight	154.09 g/mol
Synonyms	Acetic Acid 1-(Trifluoromethyl)Ethenyl Ester; 1-Trifluoromethylvinyl Acetate; 2-Acetoxy-1,1,1-trifluoroethylene; 1,1,1-Trifluoro-2-acetoxyethylene; Vinyl Acetate, 1-(Trifluoromethyl)-; TFVA; 2247-91-8 (CAS)
EINECS	Contact for details

Quality Control

Our 1-(Trifluoromethyl)Vinyl Acetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at 2-8°C (refrigerated) or as specified on the label. Due to its hygroscopic and highly volatile nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.