Description

(E)-4-Phenyl-But-2-Enoic Acid is a high-purity, unsaturated carboxylic acid derivative featuring a conjugated system with a phenyl substituent. This compound is a versatile and valuable chemical intermediate in advanced organic synthesis, prized for its defined stereochemistry and reactive alkene functionality. It is primarily utilized by pharmaceutical research and fine chemical industries for the development of active pharmaceutical ingredients (APIs), fragrances, and liquid crystal materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of prostaglandins, anti-inflammatory agents, and other bioactive molecules.
• Organic Synthesis: Used in Heck reactions, Michael additions, and other coupling reactions to construct complex molecular architectures.
• Liquid Crystal & OLED Materials: Serves as a precursor for mesogenic compounds and electron-transport materials in display technologies.
• Fragrance & Flavor Chemistry: An intermediate in the production of certain aromatic compounds and flavoring agents.
• Agrochemical Research: Employed in the development of novel herbicides and plant growth regulators.
• Academic & R&D: A valuable reagent for methodological studies in synthetic organic chemistry and catalysis.

Basic Information

Product Name	(E)-4-Phenyl-But-2-Enoic Acid
CAS No.	2243-52-9
Molecular Formula	C10H10O2
Molecular Weight	162.19 g/mol
Synonyms	(E)-4-Phenylbut-2-enoic acid; trans-4-Phenyl-2-butenoic acid; (E)-3-Carboxy-1-phenyl-1-propene; trans-Cinnamylacetic acid; (E)-4-Phenyl-2-butenoic acid; 4-Phenyl-trans-2-butenoic acid; (2E)-4-Phenyl-2-butenoic acid; Phenylbutenoic acid
EINECS	218-816-3

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity. Our (E)-4-Phenyl-But-2-Enoic Acid is produced and tested in facilities adhering to cGMP principles. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request. Our quality commitment ensures the material meets the exacting standards required for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider storing under an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	136 - 140 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.