Description

2',4'-Dichloroacetophenone is a versatile chlorinated aromatic ketone serving as a critical building block in advanced organic synthesis. Its value lies in its reactive carbonyl and halogen groups, which enable precise chemical transformations for creating complex molecular architectures. This high-purity intermediate is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with halogenated aromatic structures.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and pesticides, leveraging its dichloro-substituted ring for bioactivity.
• Organic Synthesis Building Block: Employed in Friedel-Crafts acylation, nucleophilic substitution, and reduction reactions to create more complex ketones, alcohols, and heterocycles.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Chemical Research & Development: A valuable standard and reagent in method development and exploratory chemistry within R&D laboratories.

Basic Information

Product Name	2',4'-Dichloroacetophenone
CAS No.	2234-16-4
Molecular Formula	C8H6Cl2O
Molecular Weight	189.04 g/mol
Synonyms	1-(2,4-Dichlorophenyl)ethanone; 2,4-Dichloroacetophenone; 2,4-Dichlorophenyl methyl ketone; Ethanone, 1-(2,4-dichlorophenyl)-; NSC 406916; α,2,4-Trichloroacetophenone (common misnomer); 2,4-DCA
EINECS	218-787-8

Quality Control

Our 2',4'-Dichloroacetophenone is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	39 - 43 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.