Description

(3R,8Aβ)-1,2,3,7,8,8A-Hexahydro-5-Hydroxy-3β,6,8,8-Tetramethyl-4H-3Aα,7α-Methanoazulene-4,9-Dione is a high-purity, complex sesquiterpenoid derivative with a unique methanoazulene core structure. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, particularly for the development of novel pharmaceutical actives and fine chemicals. It is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require structurally defined, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel drug candidates, particularly in steroid-like or terpenoid-based therapeutic development.
• Agrochemical Synthesis: Used as a building block for creating advanced active ingredients with specific biological activity.
• Fine Chemical Production: Serves as a sophisticated starting material or intermediate in the manufacture of specialty chemicals, flavors, and fragrances.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, asymmetric synthesis, and natural product total synthesis.
• Material Science Research: Potential precursor for developing novel organic materials with specific optical or electronic properties due to its complex conjugated system.

Basic Information

Product Name	(3R,8Aβ)-1,2,3,7,8,8A-Hexahydro-5-Hydroxy-3β,6,8,8-Tetramethyl-4H-3Aα,7α-Methanoazulene-4,9-Dione
CAS No.	2211-20-3
Molecular Formula	C₁₅H₂₀O₃
Molecular Weight	248.32 g/mol
Synonyms	5-Hydroxy-3,6,8,8-tetramethyl-4,9-dioxo-1,2,3,7,8,8a-hexahydro-3a,7-methanoazulene; 3,6,8,8-Tetramethyl-1,2,3,7,8,8a-hexahydro-5-hydroxy-3a,7-methanoazulene-4,9-dione; 5-Hydroxy-3,6,8,8-tetramethyl-4,9-dioxo-1,2,3,7,8,8a-hexahydro-3a,7-methanoazulene; (3R,8aβ)-1,2,3,7,8,8a-Hexahydro-5-hydroxy-3,6,8,8-tetramethyl-4H-3a,7-methanoazulene-4,9-dione; A sesquiterpenoid dione derivative.
EINECS	Contact for details

Quality Control

Our production of (3R,8Aβ)-1,2,3,7,8,8A-Hexahydro-5-Hydroxy-3β,6,8,8-Tetramethyl-4H-3Aα,7α-Methanoazulene-4,9-Dione adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.