Description

2-Ethoxy-4,4,5,5-tetramethyl-1,3-dioxolane is a specialized cyclic acetal derivative, valued for its unique chemical structure as a protected carbonyl equivalent and a versatile building block in organic synthesis. Its primary commercial importance lies in its role as a key intermediate for the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical industries. This compound is essential for research chemists and production facilities engaged in developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block in multi-step synthesis for novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for fragrances, flavors, and specialty performance chemicals.
• Polymer & Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers and resins.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for constructing complex molecular architectures, often as a protecting group or chiral auxiliary.
• Chemical Research: Utilized in methodological development and as a standard in analytical chemistry.

Basic Information

Product Name	2-Ethoxy-4,4,5,5-Tetramethyl-1,3-Dioxolane
CAS No.	2203-73-8
Molecular Formula	C9H18O3
Molecular Weight	174.24 g/mol
Synonyms	2-Ethoxy-4,4,5,5-tetramethyl-1,3-dioxolane; 1,3-Dioxolane, 2-ethoxy-4,4,5,5-tetramethyl-; Ethyl 2,2,3,3-tetramethyl-1,3-dioxolane-4-carboxylate (common misnomer); 4,4,5,5-Tetramethyl-2-ethoxy-1,3-dioxolane; Pinacolone ethylene ketal ethyl ether; Acetone pinacolone cyclic ketal ethyl ether
EINECS	218-626-5

Quality Control

Our 2-Ethoxy-4,4,5,5-tetramethyl-1,3-dioxolane is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for production where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. Containers should be kept tightly sealed when not in use to prevent evaporation and potential contamination.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20/D)	1.420 - 1.425
Density (g/mL at 20°C)	0.950 - 0.980

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.