Description

3-(Trifluoromethyl)Phenoxyacetonitrile is a versatile fluorinated aromatic nitrile building block, essential for advanced organic synthesis. Its core value lies in the trifluoromethylphenoxy moiety, which imparts unique physicochemical properties like enhanced lipophilicity and metabolic stability to target molecules. This high-purity intermediate is critically needed by R&D and production chemists in the pharmaceutical and agrochemical industries for constructing complex active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides and pesticides, where the CF3 group improves bioactivity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for display technologies.
• Functional Polymer Modifier: Incorporated into polymer backbones to enhance chemical resistance, thermal stability, and surface properties.
• Organic Electronic Materials: Building block for electron-transport materials and other components in OLEDs and organic photovoltaics.
• Chemical Research & Development: A valuable reagent for exploring new fluorination chemistry and creating compound libraries for screening.

Basic Information

Product Name	3-(Trifluoromethyl)Phenoxyacetonitrile
CAS No.	2145-31-5
Molecular Formula	C9H6F3NO
Molecular Weight	201.15 g/mol
Synonyms	m-(Trifluoromethyl)phenoxyacetonitrile; (3-Trifluoromethylphenoxy)acetonitrile; 2-[(3-Trifluoromethyl)phenoxy]acetonitrile; α-((3-(Trifluoromethyl)phenoxy)acetonitrile; Acetonitrile, [(3-(trifluoromethyl)phenoxy]-; 3-Trifluoromethylphenoxyacetonitrile; Phenoxyacetonitrile, 3-(trifluoromethyl)-; 2145-31-5
EINECS	218-413-4

Quality Control

Our 3-(Trifluoromethyl)Phenoxyacetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.