Description

(3E)-4-(2-Fluorophenyl)But-3-En-2-One is a high-purity fluorinated organic building block of significant interest in advanced synthetic chemistry. This compound serves as a versatile intermediate for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and functional materials. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorinated phenyl motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorophenyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic components for electronic display materials and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions such as Heck, Suzuki, and Stille couplings for carbon-carbon bond formation.
• Flavor & Fragrance Chemistry: Employed in the synthesis of complex aromatic molecules for high-value fragrance and flavor ingredients.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry within R&D laboratories.

Basic Information

Item	Details
Product Name	(3E)-4-(2-Fluorophenyl)But-3-En-2-One
CAS No.	2143-80-8
Molecular Formula	C10H9FO
Molecular Weight	164.18 g/mol
Synonyms	(E)-4-(2-Fluorophenyl)-3-buten-2-one; 1-(2-Fluorophenyl)-1-buten-3-one; 2-Fluorobenzylideneacetone; (E)-4-(2-Fluorophenyl)but-3-en-2-one; 3-Buten-2-one, 4-(2-fluorophenyl)-, (3E)-; 4-(2-Fluorophenyl)-3-buten-2-one; (E)-1-(2-Fluorophenyl)-1-buten-3-one
EINECS	Contact for details

Quality Control

Our (3E)-4-(2-Fluorophenyl)But-3-En-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and FTIR to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.