Description

2,3,5,6-Tetramethylacetophenone is a high-purity, substituted acetophenone derivative characterized by its unique tetramethylated aromatic ring structure. This compound serves as a critical advanced intermediate in the synthesis of complex organic molecules, offering precise steric and electronic properties for fine-tuning product performance. It is primarily utilized by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Precursor: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and other advanced polymeric materials.
• Fragrance and Flavor Chemistry: Acts as an intermediate for synthesizing specific musk-like or woody aroma chemicals due to its substituted acetophenone backbone.
• Organic Synthesis Building Block: Provides a sterically hindered ketone functionality for constructing complex molecular architectures in academic and industrial research.

Basic Information

Product Name	2,3,5,6-Tetramethylacetophenone
CAS No.	2142-79-2
Molecular Formula	C12H16O
Molecular Weight	176.26 g/mol
Synonyms	1-(2,3,5,6-Tetramethylphenyl)ethanone; 2,3,5,6-Tetramethylacetophenone; 2',3',5',6'-Tetramethylacetophenone; Acetophenone, 2,3,5,6-tetramethyl-; Ethanone, 1-(2,3,5,6-tetramethylphenyl)-; Durenyl methyl ketone
EINECS	218-387-9

Quality Control

Our 2,3,5,6-Tetramethylacetophenone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our quality commitment supports applications requiring high-purity intermediates for research and regulated production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.