Description

2-(2-Hydroxy-1,1,1,3,3,3-Hexafluoropropyl)-1-Naphthol is a specialized fluorinated naphthol derivative that serves as a high-value intermediate in advanced chemical synthesis. Its unique structure, featuring both a hexafluoroisopropyl alcohol moiety and a naphthol ring, makes it a critical building block for creating materials with enhanced thermal stability, chemical resistance, and specific optical properties. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging fluorine's ability to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in developing next-generation herbicides, fungicides, and pesticides where the fluorinated segment can enhance lipophilicity and environmental persistence.
• Advanced Material Monomer: Serves as a monomer or co-monomer for synthesizing specialty polymers, including fluorinated polyesters, polycarbonates, and epoxy resins with improved performance characteristics.
• Liquid Crystal & OLED Materials: A valuable building block for creating fluorinated components in liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs) due to its impact on dielectric constant and molecular alignment.
• Ligand for Catalysis: Can be utilized to develop novel chiral or fluorinated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Surface Modification Agent: Imparts hydrophobic and oleophobic properties to surfaces when used as a coating additive or grafting agent.

Basic Information

Product Name	2-(2-Hydroxy-1,1,1,3,3,3-Hexafluoropropyl)-1-Naphthol
CAS No.	2092-87-7
Molecular Formula	C₁₄H₁₀F₆O₂
Molecular Weight	324.22 g/mol
Synonyms	1-Naphthol, 2-(1-hydroxy-2,2,2-trifluoro-1-trifluoromethylethyl)-; 2-(1-Hydroxy-2,2,2-trifluoro-1-trifluoromethylethyl)-1-naphthol; 2-(2-Hydroxy-1,1,1,3,3,3-hexafluoro-2-propyl)-1-naphthol; Hexafluoroisopropanol Naphthol Derivative; HFIP-Naphthol; 1-Naphthol, 2-(hexafluoro-2-hydroxyisopropyl)-; α-(1-Hydroxy-2-naphthyl)hexafluoroisopropanol
EINECS	Contact for details

Quality Control

Our production of 2-(2-Hydroxy-1,1,1,3,3,3-Hexafluoropropyl)-1-Naphthol adheres to a strict quality management system to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We support compliance with global regulatory frameworks, including REACH, and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.