Description

4'-tert-Butyl-2',6'-Dimethylacetophenone is a specialized aromatic ketone derivative, serving as a crucial intermediate in advanced organic synthesis. Its sterically hindered structure makes it particularly valuable for the development of fine chemicals and functional materials where specific molecular architecture is required. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to build complex molecular frameworks.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a bulky, substituted acetophenone core.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators where its tert-butyl and dimethyl groups impart specific biological activity and stability.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical Production: Intermediate in the manufacture of dyes, pigments, UV stabilizers, and other performance chemicals.
• Polymer & Material Science: Used in the synthesis of monomers for specialty polymers, including high-performance resins and engineering plastics.
• Fragrance & Flavor Ingredient Synthesis: Acts as a precursor for certain musk-like or woody fragrance compounds due to its aromatic ketone structure.
• Research & Development: A valuable tool for academic and industrial research in organic chemistry, medicinal chemistry, and material science.

Basic Information

Product Name	4'-tert-Butyl-2',6'-Dimethylacetophenone
CAS No.	2040-10-0
Molecular Formula	C14H20O
Molecular Weight	204.31 g/mol
Synonyms	1-(4-tert-Butyl-2,6-dimethylphenyl)ethanone; 4'-tert-Butyl-2',6'-dimethylacetophenone; 2',6'-Dimethyl-4'-tert-butylacetophenone; 1-[4-(1,1-Dimethylethyl)-2,6-dimethylphenyl]ethanone; 4-(1,1-Dimethylethyl)-2,6-dimethylacetophenone; p-tert-Butyl-2,6-dimethylacetophenone; Acetophenone, 4'-tert-butyl-2',6'-dimethyl-
EINECS	Contact for details

Quality Control

Our 4'-tert-Butyl-2',6'-Dimethylacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and other relevant quality frameworks for industrial and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.