Description

Ethyl 2-Bromo-3-Methyl-4,4,4-Trifluorobutyrate is a high-value fluorinated organic building block characterized by its reactive bromine and ester functionalities. This compound is essential for introducing the trifluoromethyl group into complex molecular architectures, a key modification for enhancing metabolic stability and lipophilicity in advanced materials. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating the trifluoromethyl group to modulate bioavailability and binding affinity.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the CF3 group contributes to improved environmental stability and efficacy.
• Material Science Research: Serves as a precursor for fluorinated monomers or polymers, contributing to materials with unique surface properties, chemical resistance, or optical characteristics.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic substitutions to construct complex, fluorinated organic molecules for various R&D applications.
• Liquid Crystal & Electronic Chemical Precursor: Potential use in the synthesis of fluorinated components for display technologies and electronic materials.

Basic Information

Product Name	Ethyl 2-Bromo-3-Methyl-4,4,4-Trifluorobutyrate
CAS No.	2024-54-6
Molecular Formula	C7H10BrF3O2
Molecular Weight	263.06 g/mol
Synonyms	2-Bromo-3-methyl-4,4,4-trifluorobutanoic acid ethyl ester; Ethyl 2-bromo-3-methyl-4,4,4-trifluorobutanoate; 4,4,4-Trifluoro-2-bromo-3-methylbutyric acid ethyl ester; Butanoic acid, 2-bromo-3-methyl-4,4,4-trifluoro-, ethyl ester; 2024-54-6; Ethyl α-bromo-β-methyl-γ,γ,γ-trifluorobutyrate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Bromo-3-Methyl-4,4,4-Trifluorobutyrate is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing including GC/HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content to ensure consistent quality and reliability for your synthetic processes. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.