Description

N,n-Dimethylformamide Dibenzyl Acetal is a specialized organo-nitrogen compound that serves as a versatile reagent and protecting group in advanced organic synthesis. Its primary value lies in its ability to act as a formyl anion equivalent or a masked aldehyde, enabling complex bond formations under controlled conditions. This high-purity intermediate is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable building blocks for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing formyl or protected aldehyde functionalities.
• Peptide Chemistry: Used as a reagent in the modification and protection of amino acids during peptide synthesis.
• Agrochemical Synthesis: Intermediate in the production of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex fragrance compounds, dyes, and specialty polymers.
• Academic & Industrial R&D: A valuable tool for methodological development in organic chemistry, including new C-C bond forming reactions.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or metal-organic frameworks (MOFs).

Basic Information

Product Name	N,n-Dimethylformamide Dibenzyl Acetal
CAS No.	2016-04-8
Molecular Formula	C18H21NO2
Molecular Weight	283.37 g/mol
Synonyms	N,N-Dimethylformamide Dibenzyl Acetal; DMF Dibenzyl Acetal; Dibenzyl (Dimethylamino)methoxymethane; α,α-Dibenzyloxy-N,N-dimethylmethanamine; (Dibenzyloxymethyl)dimethylamine; N,N-Dimethyl-O,O-dibenzylformamidine Acetal; Formamidine, N,N-dimethyl-, dibenzyl acetal
EINECS	Contact for details

Quality Control

Our N,n-Dimethylformamide Dibenzyl Acetal is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to confirm identity and quantify impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications. We support cGMP and ISO 9001 standards for quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and oxidizing agents. Due to its sensitivity, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after initial opening to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.