Description

Ethyl Diazoacetoacetate is a versatile and highly reactive diazo compound, primarily valued as a key building block in organic synthesis. Its unique structure allows it to participate in a range of cycloaddition and carbene insertion reactions, enabling the efficient construction of complex heterocyclic frameworks. This makes it an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various heterocyclic compounds, including pyrazoles and pyrazolones, which are core structures in many active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its reactivity is leveraged to create novel molecular scaffolds with specific biological activity.
• Fine Chemical Manufacturing: Serves as a versatile reagent for the preparation of dyes, pigments, and other specialty organic compounds requiring diazo functionality.
• Academic & R&D: A valuable tool in research laboratories for method development in organic synthesis, particularly in studies involving cyclopropanation and C-H functionalization.
• Material Science Precursor: Potential use in the synthesis of polymers and advanced materials with tailored properties through controlled polymerization or cross-linking reactions.

Basic Information

Product Name	Ethyl Diazoacetoacetate
CAS No.	2009-97-4
Molecular Formula	C6H8N2O3
Molecular Weight	156.14 g/mol
Synonyms	Ethyl 2-diazoacetoacetate; Diazoacetoacetic Acid Ethyl Ester; Ethyl Diazoacetoacetate; Ethyl 2-Diazo-3-oxobutanoate; Acetoacetic acid, 2-diazo-, ethyl ester; Ethyl α-diazoacetoacetate; 2-Diazo-3-oxobutanoic acid ethyl ester; Ethyl (diazoacetyl)acetate
EINECS	217-925-6

Quality Control

Our Ethyl Diazoacetoacetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality management system is designed to meet the stringent requirements of research and industrial-scale synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated). Due to its light-sensitive and potentially unstable diazo nature, prolonged storage at room temperature or exposure to heat and direct light should be avoided. Keep away from sources of ignition, strong acids, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange liquid or crystalline mass
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.