Description

4-Benzyloxy-2,6-Difluoro-Benzoic Acid is a high-purity, fluorinated benzoic acid derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of fluorine atoms and a benzyl-protected phenolic group, enabling precise molecular modifications for developing novel compounds. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and fine chemicals requiring specific fluorinated aromatic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides where the difluoro-benzoic acid core enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Advanced Polymer Modification: Employed to introduce fluorine and benzoic acid functionalities into polymer chains, altering material properties like chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new fluorination reactions and constructing complex molecular architectures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	4-Benzyloxy-2,6-Difluoro-Benzoic Acid
CAS No.	1993479-31-4
Molecular Formula	C14H10F2O3
Molecular Weight	264.23 g/mol
Synonyms	2,6-Difluoro-4-(phenylmethoxy)benzoic Acid; Benzoic acid, 4-(benzyloxy)-2,6-difluoro-; 4-(Benzyloxy)-2,6-difluorobenzoic Acid; 4-(Phenylmethoxy)-2,6-difluorobenzoic Acid; 2,6-Difluoro-4-benzyloxybenzoic Acid; 4-O-Benzyl-2,6-difluorobenzoic Acid
EINECS	Contact for details

Quality Control

Our 4-Benzyloxy-2,6-Difluoro-Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.