Description

Potassium (2-Chloropyridin-4-Yl)Trifluoroborate is a high-value organotrifluoroborate salt, a crucial building block in modern synthetic chemistry. Its primary value lies in its exceptional stability and reactivity, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex pyridine-containing molecules for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate Synthesis: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing functionalized pyridine scaffolds.
• Agrochemical Development: Used to create novel herbicides, fungicides, and insecticides by introducing the 2-chloropyridin-4-yl moiety into target molecules.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant boronic acid equivalent for palladium-catalyzed carbon-carbon bond formation.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysis, and metal-organic frameworks (MOFs).
• Chemical Biology & Medicinal Chemistry: Utilized in the discovery and optimization of drug candidates through structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and custom synthesis organizations serving the life sciences sector.

Basic Information

Product Name	Potassium (2-Chloropyridin-4-Yl)Trifluoroborate
CAS No.	1992782-05-4
Molecular Formula	C5H3BClF3KN
Molecular Weight	213.44 g/mol
Synonyms	Potassium (2-Chloro-4-pyridyl)trifluoroborate; 2-Chloro-4-pyridyltrifluoroborate Potassium Salt; (2-Chloropyridin-4-yl)trifluoroboronic Acid Potassium Salt; Potassium 2-Chloropyridine-4-trifluoroborate; 4-(Potassiumtrifluoroboratomethyl)-2-chloropyridine; Potassium Trifluoro(2-chloro-4-pyridinyl)borate; K-2-Chloro-4-Pyridyltrifluoroborate; 2-Chloro-4-pyridinyltrifluoroborate potassium
EINECS	Contact for details

Quality Control

Our Potassium (2-Chloropyridin-4-Yl)Trifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 13C, 19F, 11B) and HPLC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
1H NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.