Description

1-(2-Amino-5-Bromo-3-Iodo-Phenyl)-Ethanone is a high-purity, multi-halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring amino, bromo, and iodo substituents, makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used as a key precursor for developing new pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers where specific halogen interactions are required.
• Cross-Coupling Reactions: The bromo and iodo substituents are excellent handles for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira, Buchwald-Hartwig) enabling rapid diversification.
• Chemical Biology: Acts as a scaffold for developing molecular probes and tags due to its derivatizable amino and halogen functional groups.
• Academic & Contract Research: A valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	1-(2-Amino-5-Bromo-3-Iodo-Phenyl)-Ethanone
CAS No.	1985633-67-7
Molecular Formula	C8H7BrINO
Molecular Weight	339.96 g/mol
Synonyms	2-Acetylamino-5-bromo-3-iodobenzene; 1-(2-Amino-5-bromo-3-iodophenyl)ethan-1-one; 5-Bromo-3-iodo-2-aminoacetophenone; 2-Amino-5-bromo-3-iodoacetophenone; Ethanone, 1-(2-amino-5-bromo-3-iodophenyl)-; AI3-73977 (Potential database ID)
EINECS	Contact for details

Quality Control

Our 1-(2-Amino-5-Bromo-3-Iodo-Phenyl)-Ethanone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant quality management standards to support our global clientele in regulated and non-regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.