Description

3-Isopropyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole CAS NO 1983152-92-6 is a high-value, organoboron-protected pyrazole derivative, serving as a critical synthetic intermediate in modern organic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and functional material development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazole or boron-based pharmacophores.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require the pyrazole moiety for biological activity.
• Material Science: Serves as a precursor for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Catalyst & Ligand Development: Employed in the design and synthesis of novel organometallic catalysts and ligands for asymmetric synthesis and polymerization processes.
• Chemical Biology Probes: Utilized in the creation of boron-containing probes for bioorthogonal chemistry and protein labeling studies.
• Academic & Industrial R&D: A versatile reagent for method development and exploring new synthetic pathways in both academic laboratories and industrial R&D centers.

Basic Information

Product Name	3-Isopropyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole
CAS No.	1983152-92-6
Molecular Formula	C11H21BN2O2
Molecular Weight	224.11 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-isopropyl-1H-pyrazole; 3-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1H-Pyrazole, 3-(1-methylethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Isopropyl-1H-pyrazole-4-boronic acid pinacol ester; 3-Isopropyl-4-(pinacolatoboryl)-1H-pyrazole; 3-Isopropyl-4-borono-1H-pyrazole pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Isopropyl-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Pyrazole is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the primary container to prevent degradation. For long-term storage, consider storing under an inert gas blanket in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.