Description

2-Chloro-6-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzoic Acid Methyl Ester is a high-value boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides by facilitating the introduction of the benzoate and chlorophenyl motifs.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create boronic acid-based probes and sensors for detecting biological analytes.
• Custom Fine Chemical Production: Acts as a versatile scaffold for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	2-Chloro-6-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzoic Acid Methyl Ester
CAS No.	1980783-96-7
Molecular Formula	C14H18BClO4
Molecular Weight	296.55 g/mol
Synonyms	Methyl 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; 2-Chloro-6-(pinacolatoboryl)benzoic Acid Methyl Ester; Methyl 2-Chloro-6-pinacolatoboronobenzoate; 1980783-96-7; Benzoic acid, 2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.