Description

6-Ethoxy-2,3,4-Trifluorobenzyl Bromide is a high-purity fluorinated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both ethoxy and trifluoromethyl substituents, makes it an essential reagent for introducing functionalized benzyl groups into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, where the fluorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Employed in the creation of specialty polymers and liquid crystals, where the benzyl bromide moiety allows for functionalization and cross-linking.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures via nucleophilic substitution reactions.
• Fluorine Chemistry: Serves as a standard substrate for studying fluorination effects and developing new synthetic methodologies in organofluorine chemistry.

Basic Information

Product Name	6-Ethoxy-2,3,4-Trifluorobenzyl Bromide
CAS No.	1980054-21-4
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	2,3,4-Trifluoro-6-ethoxybenzyl Bromide; 1-(Bromomethyl)-2-ethoxy-3,4,5-trifluorobenzene; (2-Ethoxy-3,4,5-trifluorophenyl)methyl Bromide; 6-Ethoxy-2,3,4-trifluorobenzylbromide; 6-Ethoxy-2,3,4-Trifluorobenzyl Bromide; 1980054-21-4; Benzene, 1-(bromomethyl)-2-ethoxy-3,4,5-trifluoro-
EINECS	Contact for details

Quality Control

Every batch of 6-Ethoxy-2,3,4-Trifluorobenzyl Bromide is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.