Description

1,7-Naphthyridine-3-Carboxaldehyde, 8-Chloro- is a high-purity, functionalized naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile aldehyde-containing intermediate, enabling the construction of complex heterocyclic scaffolds essential for pharmaceutical and agrochemical discovery. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors, antiviral agents, and anti-cancer compounds targeting the naphthyridine pharmacophore.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the chlorinated naphthyridine core provides specific biological activity.
• Ligand Synthesis: The aldehyde functional group allows for the creation of chelating ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science: Serves as a building block for organic electronic materials, such as semiconductors and light-emitting compounds, due to its rigid, conjugated structure.
• Chemical Biology Probes: Utilized in the design and synthesis of fluorescent tags or molecular probes for studying biological processes.

Basic Information

Product Name	1,7-Naphthyridine-3-Carboxaldehyde, 8-Chloro-
CAS No.	1956389-95-9
Molecular Formula	C9H5ClN2O
Molecular Weight	192.60 g/mol
Synonyms	8-Chloro-1,7-naphthyridine-3-carboxaldehyde; 8-Chloro-1,7-naphthyridine-3-carbaldehyde; 8-Chloro-1,7-naphthyridine-3-carboxaldehyde; 8-Chloro-1,7-naphthyridin-3-yl)methanal; 1956389-95-9; 8-Chloro-1,7-naphthyridine-3-carboxylic aldehyde; 3-Formyl-8-chloro-1,7-naphthyridine
EINECS	Contact for details

Quality Control

Our 1,7-Naphthyridine-3-Carboxaldehyde, 8-Chloro- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications in GLP and cGMP environments, ensuring reliable performance in your most sensitive research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity for oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.