Description

1-Methyl-5-Phenyl-1H-1,2,4-Triazole-3-Carbaldehyde is a high-purity, functionalized triazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile aldehyde-containing intermediate, enabling the construction of complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for lead optimization and scale-up.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinases, enzymes, and receptors where the triazole core is pharmacologically active.
• Agrochemical Synthesis: Used in the development of new generation fungicides, herbicides, and plant growth regulators that incorporate the 1,2,4-triazole moiety.
• Coordination Chemistry & Ligand Design: The aldehyde and triazole functional groups make it a valuable starting material for creating chelating ligands used in catalysis and material science.
• Material Science Research: Employed in the synthesis of organic semiconductors, metal-organic frameworks (MOFs), and polymers with specific electronic or photophysical properties.
• Chemical Biology Probes: Useful for synthesizing tagged molecules and probes for studying biological processes and target engagement.

Basic Information

Product Name	1-Methyl-5-Phenyl-1H-1,2,4-Triazole-3-Carbaldehyde
CAS No.	1956335-99-1
Molecular Formula	C10H9N3O
Molecular Weight	187.20 g/mol
Synonyms	1-Methyl-5-phenyl-1H-1,2,4-triazole-3-carboxaldehyde; 3-Formyl-1-methyl-5-phenyl-1,2,4-triazole; 5-Phenyl-1-methyl-1H-1,2,4-triazole-3-carbaldehyde; 1-Methyl-5-phenyl-1,2,4-triazole-3-carbaldehyde; 1-Methyl-5-phenyl-1,2,4-triazol-3-yl-carbaldehyde; 1-Methyl-5-phenyl-v-triazole-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-Phenyl-1H-1,2,4-Triazole-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.