Description

6,6-Difluorobicyclo[3.1.0]Hexan-3-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique strained bicyclic scaffold with strategic fluorine substitution. This compound is of significant value for medicinal chemistry research and development, enabling the exploration of novel bioactive molecules with enhanced metabolic stability and binding affinity. It is primarily sought after by R&D teams and process chemists in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to introduce conformational constraint and fluorine atoms into lead compounds.
• Agrochemical Synthesis: Serves as a precursor for developing new generation pesticides and herbicides with improved efficacy.
• Chemical Biology Probe Development: Utilized in the creation of molecular probes for studying enzyme mechanisms and biological pathways.
• Process Development & Scale-up: Employed in optimizing synthetic routes for the commercial production of fine chemicals.

Basic Information

Product Name	6,6-Difluorobicyclo[3.1.0]Hexan-3-Amine Hydrochloride
CAS No.	1955524-13-6
Molecular Formula	C7H10ClF2N
Molecular Weight	181.61 g/mol
Synonyms	3-Amino-6,6-difluorobicyclo[3.1.0]hexane hydrochloride; 6,6-Difluoro-3-aminobicyclo[3.1.0]hexane HCl; Bicyclo[3.1.0]hexan-3-amine, 6,6-difluoro-, hydrochloride (1:1); 1955524-13-6; 6,6-Difluorobicyclo[3.1.0]hexan-3-amine HCl; 3-Bicyclo[3.1.0]hexylamine, 6,6-difluoro-, hydrochloride
EINECS	Contact for details

Quality Control

Our 6,6-Difluorobicyclo[3.1.0]Hexan-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.