Description

1-(Fluoromethyl)-2-Azabicyclo[2.1.1]Hexane Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique, strained bicyclic scaffold. This compound matters as a critical building block for medicinal chemists, enabling the synthesis of novel drug candidates with potential for enhanced metabolic stability and target engagement. It is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors, particularly those focused on developing new central nervous system (CNS) agents, enzyme inhibitors, and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a constrained scaffold to explore structure-activity relationships (SAR) and improve drug-like properties such as potency and selectivity.
• Preclinical Drug Development: Employed in the synthesis of candidate compounds for pharmacological screening and toxicology studies.
• Chemical Biology Probes: Acts as a core structure for developing tool compounds to study biological pathways and target validation.
• Process Chemistry: Utilized in route scouting and optimization for the scalable synthesis of complex drug molecules.

Basic Information

Product Name	1-(Fluoromethyl)-2-Azabicyclo[2.1.1]Hexane Hydrochloride
CAS No.	1955507-12-6
Molecular Formula	C7H13ClFN
Molecular Weight	165.64 g/mol
Synonyms	1-(Fluoromethyl)-2-azabicyclo[2.1.1]hexane hydrochloride; 2-Azabicyclo[2.1.1]hexane, 1-(fluoromethyl)-, hydrochloride (1:1); 1-(Fluoromethyl)-2-azabicyclo[2.1.1]hexane HCl; (1R,4S)-1-(Fluoromethyl)-2-azabicyclo[2.1.1]hexane hydrochloride (if applicable to specific stereoisomer); 1955507-12-6; Fluoromethyl azabicyclohexane hydrochloride; Azabicyclo[2.1.1]hexane fluoromethyl hydrochloride
EINECS	Contact for details

Quality Control

Our 1-(Fluoromethyl)-2-Azabicyclo[2.1.1]Hexane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.