Description

1H-Pyrazole-4-Carboxaldehyde, 5-Iodo-1-(1-Methylethyl)- is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique structure, featuring both an aldehyde and an iodo-substituent on a pyrazole core, makes it a versatile precursor for constructing complex molecules via cross-coupling and condensation reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and scale-up of new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical scaffold in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used as a key building block for developing new generation herbicides, fungicides, and insecticides with improved efficacy.
• Ligand Synthesis: The aldehyde and halogen functionalities allow for the creation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and protein interactions.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodo-substituent is highly reactive in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) for carbon-carbon bond formation.

Basic Information

Product Name	1H-Pyrazole-4-Carboxaldehyde, 5-Iodo-1-(1-Methylethyl)-
CAS No.	1946822-59-8
Molecular Formula	C7H9IN2O
Molecular Weight	264.07 g/mol
Synonyms	5-Iodo-1-isopropyl-1H-pyrazole-4-carboxaldehyde; 1-Isopropyl-5-iodo-1H-pyrazole-4-carbaldehyde; 5-Iodo-1-(propan-2-yl)-1H-pyrazole-4-carboxaldehyde; 1H-Pyrazole-4-carboxaldehyde, 5-iodo-1-(1-methylethyl)-; Isopropyl-5-iodopyrazole-4-carboxaldehyde; 5-Iodo-1-isopropylpyrazole-4-carbaldehyde; 1-(1-Methylethyl)-5-iodo-1H-pyrazole-4-carboxaldehyde
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrazole-4-Carboxaldehyde, 5-Iodo-1-(1-Methylethyl)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and development. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.