Description

1-(Chloromethyl)-4-Ethoxy-2-Fluorobenzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a reactive chloromethyl group and a fluorine substituent, makes it a versatile intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine atom and benzyl chloride moiety are critical for biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic compounds used in electronic displays and optoelectronic devices.
• Cross-Coupling Reactions: The chloromethyl group can be utilized in various palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Functional Polymer Monomer: Acts as a monomer or modifier in the synthesis of specialty polymers with unique thermal or chemical resistance properties.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial laboratories.

Basic Information

Product Name	1-(Chloromethyl)-4-Ethoxy-2-Fluorobenzene
CAS No.	1935948-33-6
Molecular Formula	C9H10ClFO
Molecular Weight	188.63 g/mol
Synonyms	4-Ethoxy-2-fluorobenzyl chloride; 2-Fluoro-4-ethoxybenzyl chloride; 1-(Chloromethyl)-4-ethoxy-2-fluorobenzene; (4-Ethoxy-2-fluorophenyl)methyl chloride; 2-Fluoro-4-ethoxybenzyl chloride; 4-Ethoxy-2-fluoro-benzylchloride; 2-Fluoro-4-ethoxybenzylchloride; 2-Fluoro-4-ethoxybenzyl chloride
EINECS	Contact for details

Quality Control

Our 1-(Chloromethyl)-4-Ethoxy-2-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profiles, and physical properties are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.