Description

Ethanone, 1-(4-Bromo-2-Fluoro-6-Methylphenyl)- is a high-purity, advanced pharmaceutical intermediate with the CAS number 1934480-39-3. This compound is a critical building block in modern organic synthesis, valued for its precise halogenated aromatic structure which enables targeted molecular modifications. It is primarily required by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated structure for enhanced bioactivity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying enzyme mechanisms and protein interactions.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing biaryl systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-fidelity bromo-fluoro intermediates.

Basic Information

Product Name	Ethanone, 1-(4-Bromo-2-Fluoro-6-Methylphenyl)-
CAS No.	1934480-39-3
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	1-(4-Bromo-2-fluoro-6-methylphenyl)ethanone; 4'-Bromo-2'-fluoro-6'-methylacetophenone; 2-Fluoro-4-bromo-6-methylacetophenone; 4-Bromo-2-fluoro-6-methylacetophenone; 1-Acetyl-4-bromo-2-fluoro-6-methylbenzene; p-Bromo-o-fluoro-m-methylacetophenone; Acetophenone, 4'-bromo-2'-fluoro-6'-methyl-
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(4-Bromo-2-Fluoro-6-Methylphenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and structural integrity suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.