Description

m-Peg3-Sulfone-Peg2-Oh CAS NO 1919045-00-3 is a specialized heterobifunctional polyethylene glycol (PEG) derivative featuring a sulfone group and a terminal hydroxyl group. This unique bifunctional structure is critical for creating stable, hydrophilic linkers in bioconjugation and pharmaceutical development. It is primarily needed by researchers and manufacturers in the fields of biopharmaceuticals, proteomics, and advanced material science for constructing next-generation therapeutics and diagnostic agents.

Application

• As a key building block for antibody-drug conjugates (ADCs) and other bioconjugates.
• Utilized in the synthesis of PEGylated small molecules and peptides to enhance solubility and pharmacokinetic properties.
• Employed as a functionalized linker in proteolysis-targeting chimeras (PROTACs) and other bifunctional molecules.
• Used in the development of hydrogel matrices and functionalized surfaces for biomedical applications.
• Serves as a spacer arm in the design of diagnostic assays and biosensors.
• Applied in polymer chemistry to introduce hydrophilic and reactive sites into copolymer structures.

Basic Information

Product Name	m-Peg3-Sulfone-Peg2-Oh
CAS No.	1919045-00-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-(2-(2-(2-Methoxyethoxy)ethoxy)ethylsulfonyl)-2-(2-(2-hydroxyethoxy)ethoxy)ethane; mPEG3-sulfone-PEG2-OH; Methoxy-PEG3-sulfone-PEG2-alcohol; Heterobifunctional PEG sulfone alcohol; PEG-based sulfone linker; Sulfone-PEG5-alcohol; 2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethylsulfonyl]ethoxy]ethanol
EINECS	Contact for details

Quality Control

Our m-Peg3-Sulfone-Peg2-Oh is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere after each use to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.