Description

Benzaldehyde, 2-Chloro-5-[2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]- is a high-value, specialty benzaldehyde derivative featuring a silyl-protected hydroxyl group, making it a critical protected intermediate in advanced organic synthesis. This compound is engineered to provide chemists with a stable, reactive handle for constructing complex molecules, particularly in pharmaceutical and agrochemical research where precise functional group manipulation is required. It is primarily sought after by R&D chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), fine chemicals, and sophisticated material precursors.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially those requiring selective deprotection and further functionalization of the hydroxyl group.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the chlorobenzaldehyde moiety contributes to biological activity.
• Fine Chemical Production: Serves as a precursor for synthesizing complex fragrance and flavor molecules, dyes, and other specialty organic compounds.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where the introduction of specific aromatic aldehydes is necessary.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, particularly in reactions involving silyl ether protection/deprotection strategies and cross-coupling reactions.

Basic Information

Product Name	Benzaldehyde, 2-Chloro-5-[2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]-
CAS No.	1911653-47-8
Molecular Formula	C15H23ClO2Si
Molecular Weight	298.88 g/mol
Synonyms	2-Chloro-5-(2-((tert-butyldimethylsilyl)oxy)ethyl)benzaldehyde; 5-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-2-chlorobenzaldehyde; 2-Chloro-5-[2-(tert-butyldimethylsilyloxy)ethyl]benzaldehyde; TBDMS-protected 2-Chloro-5-(2-hydroxyethyl)benzaldehyde; tert-Butyldimethyl[2-(4-chloro-3-formylphenoxy)ethyl]silane; [2-(3-Formyl-4-chlorophenoxy)ethyl](tert-butyl)dimethylsilane
EINECS	Contact for details

Quality Control

Our production of Benzaldehyde, 2-Chloro-5-[2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]ethyl]- adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.