Description

2-Methyl-4-Methylthiophenylboronic Acid Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. Its value lies in its stability and reactivity as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and fine chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds in the synthesis of biaryl and heterobiaryl compounds.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing thioether and substituted phenyl motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with tailored properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organometallic complexes.
• Material Science Research: A precursor for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for studying biological systems and mechanisms.

Basic Information

Product Name	2-Methyl-4-Methylthiophenylboronic Acid Pinacol Ester
CAS No.	1899905-99-7
Molecular Formula	C14H21BO2S
Molecular Weight	264.19 g/mol
Synonyms	2-Methyl-4-(methylthio)benzeneboronic Acid Pinacol Ester; 4-Methylthio-2-methylphenylboronic Acid Pinacol Ester; (2-Methyl-4-(methylthio)phenyl)boronic Acid Pinacol Ester; 2-Methyl-4-methylthiophenylboronic Acid Neopentyl Glycol Ester (common alternative); Pinacol (2-Methyl-4-(methylthio)phenyl)boronate; Boronic acid, B-[2-methyl-4-(methylthio)phenyl]-, 1,1,1-trimethylethylene ester; CAS 1899905-99-7.
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-Methylthiophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with lot-specific data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.