Description

3,3,3-Trifluoro-2,2-dimethylpropan-1-ol is a high-value fluorinated alcohol building block characterized by its unique combination of a tertiary carbon center and a trifluoromethyl group. This structure imparts significant lipophilicity and metabolic stability, making it a critical intermediate for advanced material and pharmaceutical synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs to improve bioavailability and binding affinity.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Polymer Modification: Incorporated into specialty polymers (e.g., polyesters, acrylates) to alter surface energy, provide oil/water repellency, and enhance chemical resistance.
• Ligand & Catalyst Design: Utilized in organometallic chemistry to create sophisticated ligands that modulate catalyst performance in asymmetric synthesis.
• Surface Active Agents: Acts as a precursor for fluorinated surfactants and coatings with low surface tension for specialized industrial applications.

Basic Information

Product Name	3,3,3-Trifluoro-2,2-dimethylpropan-1-ol
CAS No.	1895296-01-1
Molecular Formula	C5H9F3O
Molecular Weight	142.12 g/mol
Synonyms	1,1,1-Trifluoro-2,2-dimethyl-3-propanol; 2,2-Dimethyl-3,3,3-trifluoropropan-1-ol; 3,3,3-Trifluoro-2,2-dimethyl-1-propanol; 3,3,3-Trifluoro-2,2-dimethylpropyl alcohol; (3,3,3-Trifluoro-2,2-dimethylpropyl) alcohol; TFDP; TFDMPA
EINECS	Contact for details

Quality Control

Our 3,3,3-Trifluoro-2,2-dimethylpropan-1-ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments. Our quality commitment supports applications requiring compliance with cGMP, ISO, and other rigorous industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.