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(E)-2-(4-(tert-Butyl)Styryl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1892603-13-2


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CAS No.:1892603-13-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(E)-2-(4-(tert-Butyl)Styryl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block designed for sophisticated organic synthesis. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules in pharmaceutical and materials research. It is an essential raw material for R&D chemists and process development scientists working in pharmaceutical intermediates, agrochemicals, and organic electronic materials.

Application

  • Pharmaceutical Intermediate Synthesis: Key building block for creating novel active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific aryl-aryl bond formations.
  • Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for synthesizing advanced organic semiconductors and emissive layer materials.
  • Polymer & Material Science: Enables the incorporation of functional styryl-boronate units into polymers for specialty coatings and advanced materials.
  • Ligand & Catalyst Development: Utilized in the synthesis of novel ligands and organometallic complexes for catalytic applications.
  • Academic & Industrial R&D: A versatile reagent for methodological development and exploring new chemical spaces in synthetic chemistry.

Basic Information

Item Details
Product Name (E)-2-(4-(tert-Butyl)Styryl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 1892603-13-2
Molecular Formula C20H31BO2
Molecular Weight 314.27 g/mol
Synonyms 4-tert-Butylstyrylboronic acid pinacol ester; (E)-4-(tert-Butyl)styrylboronic acid pinacol ester; (E)-2-[2-[4-(tert-Butyl)phenyl]ethenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-tert-Butyl-trans-styrylboronic acid pinacol ester; trans-2-(4-tert-Butylstyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (E)-4-tert-ButylstyrylBpin; (E)-2-(4-(tert-Butyl)styryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Quality Control

Our (E)-2-(4-(tert-Butyl)Styryl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure high chemical purity and isomeric integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon/nitrogen) for long-term storage and when dispensing to maintain optimal purity and reactivity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0% (Area %)
Isomeric Purity (E/Z Ratio) ≥ 98:2 (by HPLC/GC)
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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