Description

2-(4-(Difluoromethyl)Phenyl)-2,2-Difluoroethanol is a high-value fluorinated aromatic building block, offering unique reactivity for the synthesis of complex molecules. This compound is critical for introducing difluoroethanol and difluoromethylphenyl motifs, which are key to modulating the physicochemical and biological properties of target compounds. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for advanced intermediate synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting metabolic and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides, where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, enhancing their chemical resistance, thermal properties, and surface characteristics.
• Organic Synthesis Reagent: A versatile reagent in medicinal chemistry for constructing complex molecular architectures via further functionalization of the alcohol group.
• Material Science Research: Investigated for developing advanced organic electronic materials and coatings due to its unique electronic properties imparted by the fluorine atoms.

Basic Information

Product Name	2-(4-(Difluoromethyl)Phenyl)-2,2-Difluoroethanol
CAS No.	1886990-13-1
Molecular Formula	C9H8F4O
Molecular Weight	208.15 g/mol
Synonyms	2,2-Difluoro-2-[4-(difluoromethyl)phenyl]ethanol; α,α-Difluoro-4-(difluoromethyl)benzenemethanol; 4-(Difluoromethyl)-α,α-difluorobenzenemethanol; 1-(4-(Difluoromethyl)phenyl)-2,2-difluoroethan-1-ol; [4-(Difluoromethyl)phenyl]difluoromethanol; DFMP-DFE
EINECS	Contact for details

Quality Control

Our 2-(4-(Difluoromethyl)Phenyl)-2,2-Difluoroethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.