Description

2-Benzyloxy-4-Cyanophenylboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its value lies in its dual functional groups, enabling precise cross-coupling reactions essential for constructing complex molecular architectures. This high-purity intermediate is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, contributing to the creation of compounds with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital building block for CDMOs and fine chemical companies offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	2-Benzyloxy-4-Cyanophenylboronic Acid
CAS No.	1884477-63-7
Molecular Formula	C14H12BNO3
Molecular Weight	253.07 g/mol
Synonyms	(2-(Benzyloxy)-4-cyanophenyl)boronic acid; 4-Cyano-2-(phenylmethoxy)benzeneboronic acid; 2-(Benzyloxy)-4-cyanobenzeneboronic acid; B-[2-(Benzyloxy)-4-cyanophenyl]boronic acid; Boronic acid, B-[2-(benzyloxy)-4-cyanophenyl]-; 2-Benzyloxy-4-cyanophenylboronic acid pinacol ester (protected form); 2-(BnO)-4-CN-PhB(OH)2
EINECS	Contact for details

Quality Control

Our 2-Benzyloxy-4-Cyanophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.