Description

(2R,3R)-2-Benzyl-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is a high-value, chiral organophosphorus compound with a complex heterocyclic structure. It serves as a crucial advanced intermediate or ligand in sophisticated synthetic chemistry, particularly in asymmetric catalysis. This product is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries who require precise stereochemical control for developing novel active ingredients and specialty materials.

Application

• Asymmetric Catalysis: As a chiral ligand or catalyst precursor in transition metal-catalyzed reactions for the synthesis of enantiomerically pure pharmaceuticals.
• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Material Science: Potential application as a monomer or additive for creating chiral polymers or advanced functional materials with specific optical properties.
• Academic & Process R&D: A valuable reagent for methodological studies in organic synthesis and process chemistry optimization within R&D laboratories.

Basic Information

Product Name	(2R,3R)-2-Benzyl-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole
CAS No.	1884457-36-6
Molecular Formula	C27H29O3P
Molecular Weight	432.49 g/mol
Synonyms	(2R,3R)-2-Benzyl-3-tert-butyl-4-(2,6-dimethoxyphenyl)-2,3-dihydro-1,3-benzoxaphosphole; (2R,3R)-2-Benzyl-3-(tert-butyl)-4-(2,6-dimethoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; 2,3-Dihydrobenzo[d][1,3]oxaphosphole, 2-benzyl-3-(1,1-dimethylethyl)-4-(2,6-dimethoxyphenyl)-, (2R,3R)-; (R,R)-2-Benzyl-3-tert-butyl-4-(2,6-dimethoxyphenyl)benzo[d][1,3]oxaphosphole; Chiral Benzoxaphosphole Ligand; P,O-Ligand
EINECS	Contact for details

Quality Control

Every batch of our (2R,3R)-2-Benzyl-3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure high chiral purity and chemical integrity, critical for sensitive catalytic and synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.