Description

3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propyl Acetate is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound is critical for enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are foundational to modern medicinal chemistry and materials science. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex molecules and novel polymers.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-boron motifs.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other functional polymers with tailored electronic properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and bioconjugates for target identification and biological pathway studies.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic routes in research laboratories.

Basic Information

Product Name	3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propyl Acetate
CAS No.	1883793-85-8
Molecular Formula	C₁₇H₂₅BO₄
Molecular Weight	304.19 g/mol
Synonyms	4-(3-Acetoxypropyl)phenylboronic acid pinacol ester; [4-(3-Acetoxypropyl)phenyl]boronic acid pinacol ester; 3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]propyl acetate; 4-(3-Acetoxypropyl)benzeneboronic acid pinacol ester; 3-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)propyl acetate; Acetic acid 3-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-propyl ester
EINECS	Contact for details

Quality Control

Our 3-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Propyl Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.