Description

Benzene, 1-Bromo-2,4-Difluoro-5-(Phenylmethoxy)- is a high-purity, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound is valued for its unique substitution pattern, which provides strategic handles for further functionalization in complex molecule assembly. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Serves as a versatile building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Liquid Crystal & OLED Material Research: Used in the development of advanced electronic materials for displays and lighting due to its fluorinated aromatic core.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Functional Polymer Monomer: Employed in the research and development of specialty polymers with tailored thermal and chemical resistance properties.
• Chemical Biology Probe Development: Acts as a scaffold for creating molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	Benzene, 1-Bromo-2,4-Difluoro-5-(Phenylmethoxy)-
CAS No.	1881293-65-7
Molecular Formula	C₁₃H₉BrF₂O
Molecular Weight	299.11 g/mol
Synonyms	1-Bromo-2,4-difluoro-5-(benzyloxy)benzene; 5-(Benzyloxy)-1-bromo-2,4-difluorobenzene; 2,4-Difluoro-5-(phenylmethoxy)bromobenzene; Benzyl 2,4-difluoro-5-bromophenyl ether; (2,4-Difluoro-5-bromophenoxy)methyl]benzene; BDFB-OBn; 1881293-65-7
EINECS	Contact for details

Quality Control

Every batch of Benzene, 1-Bromo-2,4-Difluoro-5-(Phenylmethoxy)- is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, GC, and NMR analysis, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request and are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.