Description

2-Bromo-4-Fluoro-3-Methoxythioanisole is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and methoxylated thioanisole structure. This compound is of significant value for its role in facilitating complex molecular transformations in synthetic organic chemistry, particularly in the construction of heterocyclic scaffolds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-infective applications.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogen and sulfur motifs for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the research of specialty polymers and liquid crystals.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic aromatic substitution due to the reactive bromo and fluoro substituents.
• Chemical Reference Standard: Utilized in analytical laboratories for method development, calibration, and quality control of related substances.

Basic Information

Product Name	2-Bromo-4-Fluoro-3-Methoxythioanisole
CAS No.	1879026-19-3
Molecular Formula	C8H8BrFOS
Molecular Weight	251.12 g/mol
Synonyms	1-Bromo-2-fluoro-3-methoxy-4-(methylthio)benzene; 2-Bromo-4-fluoro-3-methoxy-1-(methylthio)benzene; 3-Bromo-1-fluoro-2-methoxy-4-(methylthio)benzene; 2-Bromo-4-fluoro-3-methoxythioanisole; Benzene, 1-bromo-2-fluoro-3-methoxy-4-(methylthio)-; 4-Fluoro-3-methoxy-2-bromothioanisole
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-3-Methoxythioanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.