Description

[1,3-Bis(2,4,6-Trimethylphenyl)Imidazolidin-2-Ylidene)-(2-I-Propoxy-5-Nitrobenzylidene) Ruthenium(Ii) Diiodide Nitro-Grela I2 is a highly specialized, second-generation ruthenium-based olefin metathesis catalyst. This compound is valued for its enhanced thermal stability and functional group tolerance, enabling more efficient and selective synthesis of complex organic molecules. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions for advanced organic synthesis and the development of novel therapeutics.

Application

• Pharmaceutical Intermediate Synthesis: Key catalyst for ring-closing metathesis (RCM) and cross-metathesis (CM) reactions in the production of active pharmaceutical ingredients (APIs).
• Fine Chemical Production: Enables the construction of complex macrocyclic and polycyclic structures for fragrances, agrochemicals, and specialty polymers.
• Academic & Industrial Research: A critical tool for methodology development in organic chemistry and materials science.
• Polymer Chemistry: Used in ring-opening metathesis polymerization (ROMP) for creating advanced functional materials with specific properties.
• Process Chemistry Optimization: Employed in scaling up synthetic routes due to its improved robustness compared to first-generation catalysts.

Basic Information

Item	Detail
Product Name	1,3-Bis(2,4,6-Trimethylphenyl)Imidazolidin-2-Ylidene)-(2-I-Propoxy-5-Nitrobenzylidene) Ruthenium(II) Diiodide Nitro-Grela I2
CAS No.	1874264-99-9
Molecular Formula	C35H41I2N3O3Ru
Molecular Weight	Contact for details
Synonyms	Nitro-Grela Catalyst; Nitro-Grela I2; Nitro-Grela 2nd Generation Catalyst; Ruthenium Nitro-Grela Catalyst; (2-I-Propoxy-5-Nitrobenzylidene)-(1,3-Bis(2,4,6-Trimethylphenyl)Imidazolidin-2-Ylidene) Ruthenium(II) Diiodide; Grela Nitro Catalyst; Hoveyda-Grubbs II Nitro Catalyst Analog
EINECS	Contact for details

Quality Control

Our high-purity metathesis catalysts are manufactured under strict quality protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, potency, and the absence of critical impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Dark green to brown solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Solubility	Soluble in common organic solvents (DCM, Toluene, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.