Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazolo[1,5-A]Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is valued for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazolo[1,5-a]pyridine cores.
• Suzuki-Miyaura Cross-Coupling: Serves as a stable, reactive boronic ester pinacol ester reagent for palladium-catalyzed C-C bond formation to create biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the discovery and synthesis of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science & OLED Development: A precursor for creating organic light-emitting diode (OLED) materials and other advanced organic electronic components.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tool compounds for biological target identification and validation.
• Academic & Contract Research: A valuable reagent for synthetic methodology development and library synthesis in academic and contract research organizations (CROs).

Basic Information

Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazolo[1,5-A]Pyridine
CAS No.	1873385-99-9
Molecular Formula	C15H21BN2O2
Molecular Weight	272.15 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazolo[1,5-a]pyridine; Pyrazolo[1,5-a]pyridine-6-boronic acid pinacol ester; 6-(Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazolo[1,5-a]pyridine; 6-Pinacolatoborylpyrazolo[1,5-a]pyridine; 6-Boronic acid pinacol ester pyrazolo[1,5-a]pyridine; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazolo[1,5-a]pyridine; CAS 1873385-99-9
EINECS	Contact for details

Quality Control

Our 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyrazolo[1,5-A]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.