Description

Cyclobutanecarboxylic Acid, 1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl Ester is a high-purity, specialized chemical building block designed for advanced synthetic applications. Its core value lies in its unique molecular architecture, which serves as a versatile intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to introduce the cyclobutane and phthalimide motifs into target structures. The CAS number for this product is 1872262-64-0.

Application

This advanced chemical intermediate is utilized in several high-value research and manufacturing processes:

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its structural complexity for enhanced biological activity.
• Organic Synthesis Reagent: Employed in academic and industrial R&D labs for constructing complex organic molecules, including natural product analogs and material science candidates.
• Proteolysis-Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of targeted protein degradation therapeutics.
• Peptide Mimetics: Incorporated into peptide backbones to confer conformational rigidity and improve metabolic stability in drug candidates.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl Ester
CAS No.	1872262-64-0
Molecular Formula	C₁₃H₁₁NO₄
Molecular Weight	245.23 g/mol
Synonyms	2-Phthalimidyl Cyclobutanecarboxylate; N-(Cyclobutanecarbonyloxy)phthalimide; Cyclobutanecarboxylic Acid Phthalimide Ester; 1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl Cyclobutanecarboxylate; Cyclobutylcarbonyl Phthalimide; Phthalimidocyclobutanecarboxylate; Cyclobutanecarboxylic Acid (1,3-Dioxo-1,3-dihydro-isoindol-2-yl) Ester
EINECS	Contact for details

Quality Control

Our production of Cyclobutanecarboxylic Acid, 1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and cGMP manufacturing. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with global regulatory frameworks, including REACH and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.